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Peptides are a class of chemically active substances linked together by amino acids using peptide bonds.http://www.ncbi.nlm.nih.gov They have specific physiological duties, including turning white fat into brown fat. Peptides work as signal molecules regulating the Neuroendocrine and metabolic system. They have been widely used in the treatment and prevention of metabolic diseases with low toxicity and low side effects.

Several peptides have become the focus of research for the potential treatment of metabolic diseases, such as diabetes and hyperlipidemia. Neuropeptide Y, adrenomedullin 2, atrial natriuretic peptide, and brain natriuretic peptide to name a few.

Peptides can further be divided into endogenous or exogenous with endogenous, being important regulators of biological processes, such as promoting energy, metabolism, and inhibiting insulin resistance.

Peptides serve an important role in inflammation, tumor development, metabolic diseases, nervous system diseases and circulatory system diseases. They function primarily through receptor binding proteins interaction and hormone activation.

Recently, several peptides have come in to consideration for the long-term treatment of obesity. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604735/table/tII-etm-0-0-09364/

Peptides encourage weight loss by promoting food satiety and increasing muscle mass. Peptides for weight loss include different growth hormone secretagogues, and receptor agonist that enhance the metabolism of food and nutrients in the body.


Sermorelin is a peptide analog, equivalent to the first 29 amino acids, of growth hormone releasing hormone. This peptide helps your pituitary gland, produce more human growth hormone naturally. it can be used to improve wound healing, reduce fat mass and increase muscle mass.

Common side effects includes irritation, itching, sensitivity, swelling pain, and redness at the injection site

Studies show that with one year of use up to 20% body fat reduction most of it being abdominal or visceral fat can be expected. Sermorelin has a very positive affect on your metabolism.

CJC-1295 is a growth hormone releasing hormone (GHRH)receptor agonist that causes prolong stimulation of growth, hormone and insulin like growth factor 1 (IGF-1)in the body . CJC – 1295. Increases metabolism assist in burning fat and increases energy while improving sleep, slowing aging and increasing bone density. It also helps in muscle building.

Ipamorelin is a highly potent ghrelin receptor agonist. It increases metabolism and growth hormone regulation. Its results are increase Fat breakdown, and energy released from the body.

MOTS-c is an exercise induced natural peptide that regulates glucose metabolism in muscles and fatty acid breakdown in the liver. This promotes weight loss prevents weight gain and provides more energy to the body.

Tesamorelin is a modified synthetic form of GHRH it regulates the release of growth hormone in the body. It can be used to decrease specifically belly fat.

PT 141 a melanocortin, a family of neuropeptides that regulate inflammatory response, fibrosis, melanogenesis, steroidogenesis, energy homeostasis, sexual function, and exocrine gland function. it is widely used in the treatment of sexual dysfunction in both men and women.

Benefits of peptides include:

 

  • Building lean muscle mass and enhancing strength
  • Slowing down the aging process
  • increasing bone density
  • preventing inflammation
  • promoting wound healing
  • improved immune system
  • Weight loss
  • improve sleep
  • improves mood
  • improve sexual function
  • increase libido
  • improve orgasms

Side effects of peptides can include:

  • headaches
  • Fluid retention
  • Itchiness at the injection site
  • Constipation
  • Hot flashes
  • Muscle pain
  • Nausea
  • Poor appetite
  • Weight gain 
  • Weight loss

peptides are not advise for those who are pregnant breast-feeding, taking certain medication’s, or with certain medical conditions. As with all information shared in this blog, you should check with your provider to see if peptide therapy is right for you.

 

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